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Ebola Pandemic ?!? Pt. 6

Discussions related to the physiological and psychological effects of peak oil on our members and future generations.

Re: Ebola possible outcomes?

Unread postby Herr Meier » Mon 13 Oct 2014, 13:28:32

Everyday that passed is closer to vaccine, cure, treatment. Nothing to worry about.
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Re: Ebola possible outcomes?

Unread postby vtsnowedin » Mon 13 Oct 2014, 18:02:14

$this->bbcode_second_pass_quote('Herr Meier', 'E')veryday that passed is closer to vaccine, cure, treatment. Nothing to worry about.
Ah but no one can know how long the journey is to that vaccine and cure. The worry is that ebola will get to your neighborhood before the cure arrives.
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Re: Ebola possible outcomes?

Unread postby AndyA » Tue 14 Oct 2014, 00:45:05

$this->bbcode_second_pass_quote('dinopello', 'W')ith smallpox, there was mandatory vaccinations, even though the vaccine was fatal for 1 in every million and had some other, more common adverse effects. If there was an ebola vaccine with similar side-effects (death being one) would people get it ?


I would not, any such assumption of safety would only be an assumption, it takes many years to test a vaccine, If I actually got ebola though I would try anything.
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Re: Ebola possible outcomes?

Unread postby AndyA » Tue 14 Oct 2014, 00:50:11

$this->bbcode_second_pass_quote('Pops', 'B')ecause people aren't very contagious until they are too sick to travel.

.

That may be true, but I think the real reason is that these people are too poor to travel, and if I was a bordering country (or any country) I would make sure that visa applications take at least 6 months. It also looks like most of the population thinks ebola is a scam by their governments to get money from the UN/IMF/WB et al. So they are pretty much 'keep calm and carry on.'
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Re: Ebola possible outcomes?

Unread postby AndyA » Tue 14 Oct 2014, 00:58:07

In 'Guns Germs and Steel' the author pointed out that some cultures are more resistant to disease then others, because they had evolutionary pressure from disease, I'd say that Africans must be likely to have the highest rates of immunity to ebola, and if for example it were to spread to Brazil it could spread quite rapidly. Pure speculation but the nurses in Spain and Dallas could very likely be of 'New World' heritage and hence have a lower level of resistance.

Does anyone understand how 'swine flu' or SARS was brought under control? I understand it was, but not exactly how.
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Re: Ebola possible outcomes?

Unread postby vtsnowedin » Tue 14 Oct 2014, 01:20:20

$this->bbcode_second_pass_quote('AndyA', '
')
Does anyone understand how 'swine flu' or SARS was brought under control? I understand it was, but not exactly how.

It burnt itself out or mutated to a milder form.
$this->bbcode_second_pass_quote('', ' ')In Philadelphia, for example, 4,597 people died in the week ending 16 October, but by 11 November, influenza had almost disappeared from the city.

http://en.wikipedia.org/wiki/1918_flu_pandemic
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Re: Ebola possible outcomes?

Unread postby Pops » Tue 14 Oct 2014, 08:45:47

Generally, I think pandemics happen because there is no "herd immunity" to whatever strain of bug - they end because of the overall increase in immunity. The H1N1 of 2009 is still around, it's just that many people have now been exposed and developed immunity to some extent.

This says a fifth of the population of the world got sick with the spanish flu in the first year or two. It had an "R" factor of 12 or something I think. Even though the stories go that you could get sick and die on your walk to work; it was that virulent, the mortality of the spanish flu was "only" 2.5% vs .1% for the "regular" flu.

Ebola's mortality is 50% so not much chance there would be a lot of the herd left if it had a R of 12 like the flu. The difference, at least from what I've read, is Ebola is not primarily respiratory - although it's kinda ambiguous, it seems like it is mostly hand-to-mouth. Flu is a respiratory disease so breathing in bugs aerosolized by a slight cough or sneeze is the perfect route to easy infection.

Add in that ebola is most contagious after symptoms appear while the flu is contagious at least a day before any symptoms appear - and the symptom in the case of the flu is a little sneeze - rather than projectile vomited blood and uncontrollable bloody diarrhea in the case of ebola.
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Re: Ebola possible outcomes?

Unread postby Subjectivist » Tue 14 Oct 2014, 09:21:34

$this->bbcode_second_pass_quote('Pops', 'G')enerally, I think pandemics happen because there is no "herd immunity" to whatever strain of bug - they end because of the overall increase in immunity. The H1N1 of 2009 is still around, it's just that many people have now been exposed and developed immunity to some extent.

This says a fifth of the population of the world got sick with the spanish flu in the first year or two. It had an "R" factor of 12 or something I think. Even though the stories go that you could get sick and die on your walk to work; it was that virulent, the mortality of the spanish flu was "only" 2.5% vs .1% for the "regular" flu.

Ebola's mortality is 50% so not much chance there would be a lot of the herd left if it had a R of 12 like the flu. The difference, at least from what I've read, is Ebola is not primarily respiratory - although it's kinda ambiguous, it seems like it is mostly hand-to-mouth. Flu is a respiratory disease so breathing in bugs aerosolized by a slight cough or sneeze is the perfect route to easy infection.

Add in that ebola is most contagious after symptoms appear while the flu is contagious at least a day before any symptoms appear - and the symptom in the case of the flu is a little sneeze - rather than projectile vomited blood and uncontrollable bloody diarrhea in the case of ebola.


Okay Pops, nice review but I don't see your prediction for how things will turn out? 8O
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Re: Ebola possible outcomes?

Unread postby Deputy Barnes » Tue 14 Oct 2014, 09:27:38

$this->bbcode_second_pass_quote('AndyA', 'I')n 'Guns Germs and Steel' the author pointed out that some cultures are more resistant to disease then others, because they had evolutionary pressure from disease, I'd say that Africans must be likely to have the highest rates of immunity to ebola, and if for example it were to spread to Brazil it could spread quite rapidly. Pure speculation but the nurses in Spain and Dallas could very likely be of 'New World' heritage and hence have a lower level of resistance.

Does anyone understand how 'swine flu' or SARS was brought under control? I understand it was, but not exactly how.


Actually several people from America have caught the disease and made fairly rapid recoveries. Kent Bradley from Texas faired much better than Thomas Duncan from Liberia. Although one might wager that Kent turned himself in at the opportune moment and got better medical care, the fact remains that whites have had much better survival rates than black Africans.

I suspect that this has something to do with the STAT2 immunity genes shared amongst Eurasians and inherited from Neanderthal. Neanderthal HLA I loci might also have something to do with it -- HLA being a key resistor of Ebola. Black people, having descended from a different strain of archaic homo, lack them.

If it is true that these paleolithic immunity genes are responsible for Caucasian immunity it would mean east Asians were immune as well -- since they possess them at even higher frequencies. I have long since suspected that this is why Ebola hasn't taken off as quickly as it should have. I do not really fear an Ebola pandemic outside of Africa but I would watch the stock market as there is a lot of panic out there.
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Re: Ebola possible outcomes?

Unread postby Pops » Tue 14 Oct 2014, 10:02:36

$this->bbcode_second_pass_quote('Subjectivist', 'O')kay Pops, nice review but I don't see your prediction for how things will turn out? 8O

I guess I really don't know, I don't have a gauge so I'd just be pulling a number out of my butt. From how it looks, the people most at risk are those dealing with people already infected, as long as it stays that way the number will be in the thousands or low 10s I'd guess. If it is more contagious than it seems to be now, or if it mutates to become more so, who knows?
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Re: Ebola possible outcomes?

Unread postby Lore » Tue 14 Oct 2014, 10:13:47

Infection is really going to come from family members helping each other. Friends helping friends.

In any case, I'm not going to worry too much about the progression of the disease till it really starts to pop up next door. Just to remain vigilant till then.
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Re: Ebola possible outcomes?

Unread postby tmazanec1 » Tue 14 Oct 2014, 10:30:39

What about many millions of Muslims in Africa dying, helping to further radicalize the Muslim world, leading to a revolution in Pakistan leading to a war with India or a Middle East war? That could light the fuse to World War Three, indirectly killing billions.
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Re: Ebola possible outcomes?

Unread postby vtsnowedin » Tue 14 Oct 2014, 11:13:08

$this->bbcode_second_pass_quote('tmazanec1', 'W')hat about many millions of Muslims in Africa dying, helping to further radicalize the Muslim world, leading to a revolution in Pakistan leading to a war with India or a Middle East war? That could light the fuse to World War Three, indirectly killing billions.

Possible I suppose . They blame the "Great Satin of the west" for every thing else. why not Ebola? If they lose millions, and I think that more then just plausible, they won't have the manpower to attack the west so probably will content themselves with killing each other just like always.
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Re: Ebola possible outcomes?

Unread postby AndyA » Tue 14 Oct 2014, 16:07:24

If we have to wait for ebola to devolve into a milder strain, that could take a while, and things will get worse before they get better. It basically means that the mortality rate will fall, making people contagious for longer. That will take years to work itself out. I have heard that before, the virus evolves favouring transmission vs mortality. So as the number of cases rises, the mortality rate will decline. A virus that kills its host too quickly doesn't get the chance to spread, so the evolutionary pressure is favouring transmission rather then mortality.

A note on mortality, just because it doesn't kill you doesn't mean you will go back to normal, all your organs are basically fucked, and your life expectancy severely reduced.

P.S. when I mentioned 'New World' I was not talking about J6P, but Native Americans from north and south America, as opposed to the European invaders who colonised the new world. So the odds of a Mexican nurse in Dallas, and an Argentinian nurse in spain are reasonable. It is just speculation, but if I was of that heritage I would be a bit more careful.
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Re: Ebola possible outcomes?

Unread postby Newfie » Tue 14 Oct 2014, 18:26:47

Deput Barnes,

Welcome aboard. Interesting first post.

Are you in this field or a casual observer/hobbyist?

My Wife was drawing the opposite conclusion, that perhaps disadvantaged folks would have been more exposed to disease and thus less susceptible.
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Re: Ebola possible outcomes?

Unread postby vtsnowedin » Tue 14 Oct 2014, 18:49:10

$this->bbcode_second_pass_quote('Deputy Barnes', '
')
Actually several people from America have caught the disease and made fairly rapid recoveries. Kent Bradley from Texas faired much better than Thomas Duncan from Liberia. Although one might wager that Kent turned himself in at the opportune moment and got better medical care, the fact remains that whites have had much better survival rates than black Africans.


I expect that the hospital facilities available and brought to bare had more to do with the outcomes then the race of the victims. If you can catch it in the early stages and spend $500,000 per patient you get better outcomes then if you misdiagnose it and wait for the projectile vomiting to begin.
Trouble is we are going to run out of money and hospital beds long before we run out of sick people.
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Re: Ebola possible outcomes?

Unread postby KaiserJeep » Tue 14 Oct 2014, 19:24:05

The PBS News Hour just reported today that revised casualty figures from the affected African countries have caused them to raise the fatality rate for Ebola infections from the prior estimate of 50% of infected persons to a new estimate that 70% of all infected people will die. The statements reported were attributed to WHO assistant director-general Bruce Aylward.

The exact updated statistics are 4,447 deaths out of 8,914 total cases. The 70% figure includes "in treatment" patients who are clearly in declining health and are not expected to recover.
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Re: Ebola possible outcomes?

Unread postby Deputy Barnes » Tue 14 Oct 2014, 19:27:42

$this->bbcode_second_pass_quote('Newfie', 'D')eput Barnes,

Welcome aboard. Interesting first post.

Are you in this field or a casual observer/hobbyist?

My Wife was drawing the opposite conclusion, that perhaps disadvantaged folks would have been more exposed to disease and thus less susceptible.


Thanks.

I'm a geneticist. I have no experience at all working in healthcare but I've been following AIDS since the 90s. It is probably true that Africans are developing some immunity to Ebola. Off of the top of my head I seem to recall that something like 10 per cent of subsaharan Africans have Ebola antibodies in any given study. HLA b loci in African blacks seem to be resistant to Ebola. Yet the bodies keep piling up. Also note that ~100 years after HIVAIDS was transmitted to humans it contiues to ravage Africa.

I never ceased to be amazed at the number of African diseases to which north Eurasians are immune to for no reason other than they inherited the outstanding immunity genes of their Neanderthal predecessors. 85 per cent of the inhabitants of Gothenburg, Sweden are totally immune to HIVAIDS due to a mutation called CCR5-Δ32, which we know was already present in western Europe during Paleolithic times. You could inject the blood of an AIDS victim in to a Swedish man's veins and there is a very high probability that he would never fall ill.

We've all been told that Native Americans were decimated by smallpox to whicn they had no immunity. I think this is a highly exagerrated excuse concocted by Leftist anthropologists like Howard Zinn, in support of their (equally exagerrated) estimation of the New World's precontact population size.

I don't buy it. For one thing, Native Americans descend fairly recently from an Old World population.At least 30% of their DNA is European, from the Neanderthaloid Aurignacians. On top of this, they are more closely related to Neanderthals than any living people on Earth. They inherited the same Ice Age immunities to these diseases and ones like them which already existed tens of thousands of years ago. So our perception of viral dynamics in the New World is contaminated by an old wive's tale that smallpox ever significantly ailed the Indians -- one for which there is little biological or historical support.

It may be true that New World Indians in Latin countries may be at increased risk for Ebola, but I would presume this is only because relatively few of these Indians are pure. Many of them are part Black or Southern European, who lack the Neanderthaloid immunity genes of their Northern relatives. Indeed Mediterraneans appear to be shifted in an African direction with regards to immunological adaptations. The blood of Latin American "Indians" is thus heavily diluted. The real Indians are actually most closely related to Nordic people as evidenced by the genomes of the unmixed Plains Indians of the USA and Canada.

The United States and Canada would seem to be fairly safe in my eyes from a pandemic, and even chaotic Mexico and Central America may be safeguarded by the Darien gap, should an outbreak swamp South America. Regrettably it will take many more cases of infection in the United States before Barack and his comrades grudgingly enforce travel bans that should have been set in place months ago. The number one obstacle to protecting the world from Ebola is a persisting refusal by Leftists to admit that shutting down borders can ever be a solution to any problem. It will cost lives.
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Re: Ebola possible outcomes?

Unread postby Deputy Barnes » Tue 14 Oct 2014, 19:45:47

$this->bbcode_second_pass_quote('KaiserJeep', 'T')he PBS News Hour just reported today that revised casualty figures from the affected African countries have caused them to raise the fatality rate for Ebola infections from the prior estimate of 50% of infected persons to a new estimate that 70% of all infected people will die. The statements reported were attributed to WHO assistant director-general Bruce Aylward.

The exact updated statistics are 4,447 deaths out of 8,914 total cases. The 70% figure includes "in treatment" patients who are clearly in declining health and are not expected to recover.


And of course even these statistics cannot take in to account the number of people in rural Africa who never saw a doctor and were merely thrown down a well or burned. The actual number of people who have died is probably in the tens of thousands. Organizations like the WHO know this and this is why they are telling us to expect 10,000 cases a week in the near future (because it's going to be happening in countries where you can't hide reality).

I would presume the actual death rate is closer to where it usually is for this disease; ~90 percent. Most of these organizations are run by incompetents who are ideologically inclined to downplay this crisis for as long as they can; to uphold the insane status quo of open borders in the developed world, because they hate it and wish to see it vanquished.
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Re: Ebola possible outcomes?

Unread postby vtsnowedin » Tue 14 Oct 2014, 20:05:20

$this->bbcode_second_pass_quote('Deputy Barnes', '[')

We've all been told that Native Americans were decimated by smallpox to whicn they had no immunity. I think this is a highly exagerrated excuse concocted by Leftist anthropologists like Howard Zinn, in support of their (equally exagerrated) estimation of the New World's precontact population size.

You should reread your history of the new world. The chronicles of the Spanish conquistadors as they swept the Caribbean and Mexico are quite clear that the diseases they brought with them killed thousands while their swords and matchlocks killed only hundreds. And it was not just small pox , measles and hopping cough and diphtheria and scarlet fever all had high death rates. In New England where my ancestors immigrated in the 1630's the native population had been greatly reduced prior to there arrival by diseases dropped off by French fur traders in Quebec and English fishing expeditions to Cape Cod. The remaining population was repeatedly struck by epidemics and the English settlers often adopted children who had lost their parents only to have them die in a latter epidemics.
While they might have shared some genetic immunity response it is clear that centuries of isolation had allowed it to decline in it's ability to withstand a unfamiliar pestilence.
After that you might read the history of Hawaii and Tahiti and research how the native populations there fared with the diseases brought to them by whaling ships.
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