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Casual Marijuana Use Causes Brain Damage

Discussions related to the physiological and psychological effects of peak oil on our members and future generations.

Re: Harvard study: casual marijuana use causes brain damage

Unread postby Rod_Cloutier » Mon 10 Nov 2014, 20:30:46

Don't take marijuana then- Ayahausca psychedelics are much safer and more rewarding:

the-ayahausca-experience-t70301.html
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Re: Harvard study: casual marijuana use causes brain damage

Unread postby Cid_Yama » Tue 11 Nov 2014, 01:14:37

What the LA Times journalist wrote was his own interpretation of the study, not what the actual study said.

$this->bbcode_second_pass_quote('', 'Q')uestions surrounding the effects of chronic marijuana use on brain structure continue to increase. To date, however, findings remain inconclusive. In this comprehensive study that aimed to characterize brain alterations associated with chronic marijuana use, we measured gray matter (GM) volume via structural MRI across the whole brain by using voxel-based morphology, synchrony among abnormal GM regions during resting state via functional connectivity MRI, and white matter integrity (i.e., structural connectivity) between the abnormal GM regions via diffusion tensor imaging in 48 marijuana users and 62 age- and sex-matched nonusing controls. The results showed that compared with controls, marijuana users had significantly less bilateral orbitofrontal gyri volume, as measured by fractional anisotropy (FA). Increased OFC functional connectivity in marijuana users was associated with earlier age of onset. Lastly, a quadratic trend was observed suggesting that the FA of the forceps minor tract initially increased following regular marijuana use but decreased with protracted regular use. This pattern may indicate differential effects of initial and chronic marijuana use that may reflect complex neuroadaptive processes in response to marijuana use. Despite the observed age of onset effects, longitudinal studies are needed to determine causality of these effects.

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The study made no conclusions as to what any of the morphological changes meant. All conclusions and speculations were that of the reporter.

The only part of the brain with less volume was the bilateral orbitofrontal gyri.
More important would be the higher functional connectivity in the orbitofrontal cortex (OFC) network, and higher structural connectivity in tracts that innervate the OFC (forceps minor).

The reporter's interpretation of that was, of course, negative, where it could just as easily be interpreted positively.

The orbitofrontal gyrus is associated with inhibition. A more accurate interpretation might be less inhibition and more conscious determination of choices.
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Re: Harvard study: casual marijuana use causes brain damage

Unread postby Plantagenet » Tue 11 Nov 2014, 01:50:02

The researchers say
$this->bbcode_second_pass_quote('', '
')we measured gray matter (GM) volume via structural MRI across the whole brain

The results showed that compared with controls, marijuana users had significantly less bilateral orbitofrontal gyro volume


Gyri are the ridges on the brain. The study found the ridges (gyro) on the pre-frontal cortex are smaller in marijuana users---thats an important discovery.

$this->bbcode_second_pass_quote('Cid Yama', '
')
The only part of the brain with less volume was the bilateral orbitofrontal gyri.


Right-O. Who the heck needs that part of their brain. :roll:

$this->bbcode_second_pass_quote('Cid Yama', ' ')A .... interpretation might be less inhibition and more conscious determination of choices.


There are four separate gyri or ridges on the pre-frontal cortex, which is responsible for a wide variety of brain functions.

There is no need to "interpret" what the brain damage caused by marijuana use produces---the study found marijuana users with shrunken gyro tended to be dumber then people who didn't smoke marijuana---pot evidently shrunk their IQs at the same time it was shrinking their brains.
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Re: Harvard study: casual marijuana use causes brain damage

Unread postby Cid_Yama » Tue 11 Nov 2014, 02:57:18

Again, morpological differences do not equate to damage. And that's Gyri as in plural for Gyrus. There is a small area of the prefrontal cortex known as the bilateral orbitofrontal gyri. Bilateral gyri as in there are two, left and right hemisphere.

The increased interconnectedness means there is more communication between the 2 hemispheres and there are more connections to the Limbic system.

As far as the brain is concerned, more connectedness generally means good.

The study said nothing about IQ. And frankly, the pot smokers I've known were of far higher IQ than the general population.

Take your nonsense elsewhere, Plant. You clearly don't know what you are talking about.
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Re: Harvard study: casual marijuana use causes brain damage

Unread postby Plantagenet » Tue 11 Nov 2014, 11:28:09

$this->bbcode_second_pass_quote('Cid_Yama', '.')...increased interconnectedness.....


???

The latest study showed Marijuana shrinks parts of the brain. There is no evidence indicating this results in increased interconnectedness as you claim.

The evidence in this study, and in prior studies done at Harvard and elsewhere, is that pot use causes reductions in IQ, and is associated with increased incidence of mental illness, including schizophrenia.
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Re: Harvard study: casual marijuana use causes brain damage

Unread postby Cid_Yama » Tue 11 Nov 2014, 12:11:10

$this->bbcode_second_pass_quote('', 'i')n regular pot smokers, that region is better connected than it is in non-users: the flow of signal traffic is speedier to other parts of that motivation and decision-making network, including across the superhighway of "white matter" that connects the brain's hemispheres.



This study did not say anything about IQ.

Get it together, Plant. Sounds like you need to light one up.
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Re: Harvard study: casual marijuana use causes brain damage

Unread postby Plantagenet » Tue 11 Nov 2014, 12:30:57

$this->bbcode_second_pass_quote('Cid_Yama', 'G')et it together, Plant. Sounds like you need to light one up.


As I said in my post, and as the title of this topic indicates, and as dozens of posts in this thread have discussed, the Harvard study and several huge epidemiological studies done in Australia, Scandinavia, etc. have shown, marijuana causes IQ losses.

Get it together, Cid. Sounds like you've lit up a few too many. :roll:
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Re: Harvard study: casual marijuana use causes brain damage

Unread postby MD » Tue 11 Nov 2014, 12:42:11

Stoners are happy to sit and chill. That should be enough of a clue right there.

Mental anesthesia. In many cases it's medically indicated, whether they've seen a doctor or not.
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Re: Harvard study: casual marijuana use causes brain damage

Unread postby yellowcanoe » Tue 11 Nov 2014, 14:19:15

$this->bbcode_second_pass_quote('pstarr', 'W')ho here hasn't smoked pot?


Not me. I only use alcohol to kill my brain cells.
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Re: Harvard study: casual marijuana use causes brain damage

Unread postby KrellEnergySource » Tue 11 Nov 2014, 16:20:31

I don't think there's been thread with more examples of confirmation bias and disconfirmation bias. Beliefs here are held more firmaly than that human affect on climate change thingy.

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Re: Harvard study: casual marijuana use causes brain damage

Unread postby hvacman » Tue 11 Nov 2014, 16:49:12

$this->bbcode_second_pass_quote('', 'I') don't think there's been thread with more examples of confirmation bias and disconfirmation bias. Beliefs here are held more firmaly than that human affect on climate change thingy.


So could we say this thread confirms your belief in the theory of confirmation/disconfirmation bias in typical online thread discussions? :) And if you are a believer in this theory, how can you be sure that your own bias towards bias theory isn't driving you to subconsciously cherry-pick "examples" of confirmation or disconfirmation bias? :-D
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Re: Harvard study: casual marijuana use causes brain damage

Unread postby Outcast_Searcher » Tue 11 Nov 2014, 16:54:09

$this->bbcode_second_pass_quote('hvacman', '')$this->bbcode_second_pass_quote('', 'I') don't think there's been thread with more examples of confirmation bias and disconfirmation bias. Beliefs here are held more firmaly than that human affect on climate change thingy.


So could we say this thread confirms your belief in the theory of confirmation/disconfirmation bias in typical online thread discussions? :) And if you are a believer in this theory, how can you be sure that your own bias towards bias theory isn't driving you to subconsciously cherry-pick "examples" of confirmation or disconfirmation bias? :-D

So we should never study or attempt to learn anything, because we might subconsciously make a mistake?

Are you comfortable in your cave, by the way, since mankind was afraid to ever venture out and learn anything needed to advance technology?

Disclosure: I couldn't care less about pot, as I don't smoke anything. As others have said, I prefer to use alcohol to kill my brain cells.
Given the track record of the perma-doomer blogs, I wouldn't bet a fast crash doomer's money on their predictions.
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Re: Harvard study: casual marijuana use causes brain damage

Unread postby Outcast_Searcher » Tue 11 Nov 2014, 16:55:21

$this->bbcode_second_pass_quote('hvacman', '')$this->bbcode_second_pass_quote('', 'I') don't think there's been thread with more examples of confirmation bias and disconfirmation bias. Beliefs here are held more firmaly than that human affect on climate change thingy.


So could we say this thread confirms your belief in the theory of confirmation/disconfirmation bias in typical online thread discussions? :) And if you are a believer in this theory, how can you be sure that your own bias towards bias theory isn't driving you to subconsciously cherry-pick "examples" of confirmation or disconfirmation bias? :-D

So we should never study or attempt to learn anything, because we might subconsciously make a mistake?

Are you comfortable in your cave, by the way, since mankind was afraid to ever venture out and learn anything needed to advance technology? Is life interesting from the safety you get hiding under your bed?

Disclosure: I couldn't care less about pot, as I don't smoke anything. As others have said, I prefer to use alcohol to kill my brain cells.
Given the track record of the perma-doomer blogs, I wouldn't bet a fast crash doomer's money on their predictions.
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Re: Harvard study: casual marijuana use causes brain damage

Unread postby Cid_Yama » Tue 11 Nov 2014, 18:03:59

Say it one more time Plant, maybe someone will believe you.
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Re: Harvard study: casual marijuana use causes brain damage

Unread postby SeaGypsy » Tue 11 Nov 2014, 18:16:46

I have been near enough to a chronic pothead for 30 years. I have had an amazing career (x3 or 4), developed several start ups which are still running, been around the world 3 times, raised 5 children (2 still in progress). My boss knows I smoke every day almost, he doesn't care, because I am his most reliable staff member. The only regular pot smoker of 35 staff, the only one in six months I have been there to not have a sick day or be less than half an hour early. I do stop smoking regularly, I find I get waves of creativity from the process of stopping & starting smoking, waves which are not there when I am either totally off weed, or chronically on it.
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Re: Harvard study: casual marijuana use causes brain damage

Unread postby dinopello » Tue 11 Nov 2014, 20:50:48

It's not the size that matters, it's how you use it.

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Re: Harvard study: casual marijuana use causes brain damage

Unread postby Plantagenet » Tue 11 Nov 2014, 21:02:26

Think of the epidemiological studies on the health effects of Marijuana the same way you'd look at the statistics on the dangers of cigarette smoking----just because the science shows there is an increase in schizophrenia or a decrease on average in the IQs of pot smokers, it doesn't mean everyone will have exactly the same response.

Some people will smoke pot with no ill effects for decades, just as some cigarette smokers live to be 90 and never get throat cancer.


I started this thread because of a new and interesting MRI studies on the effects of marijuana smoking on the brain done at the Harvard Medical School. Their data clearly showed that marijuana causes brain damage---their MRI images showed that smoking pot causes various parts of the brain to shrink and become distorted. Now in this more recent study, published in PNAS (Proceedings of the National Academy of Sciences), better MRI imagine shows that the brain gyrus structures are smaller in marijuana smokers. This fits with studies on mice that show that marijuana smoke cause the mice brains to shrink.

Why is this important?

The gyrus are the ridges and wrinkles on the surface of the brain. A lot of data shows that smarter people have bigger gyrus structures and deeper folds. Anything that causes the wrinkles on the brain to shrink is very dangerous. In fact, people who don't have normal size gyrus structures are often severely retarded.

For instance:

We have lots of evidence that gyri and sulci are positively linked to intelligence. (Remember, more wrinkles = more neurons.) Human brains are wrinklier than the brains of any other animal. For the most part, we’re all as wrinkly as the next person, but not always. Some people are born with a condition called lissencephaly. This means “smooth brain.” It causes severe mental retardation

from the brain geek: folds-of-brain

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Re: Harvard study: casual marijuana use causes brain damage

Unread postby Plantagenet » Tue 11 Nov 2014, 21:04:45

$this->bbcode_second_pass_quote('dinopello', 'I')t's not the size that matters, it's how you use it.


Image

Great post, dino.

Notice the elephant brain is pretty smooth, i.e. it doesn't have big wrinkles (gyrus) like the human brain.

Its not the size that matters, its how large and well developed the gyrus and sulci are.
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