[vision-master]

$this->bbcode_second_pass_quote('', '"')We now think that people with naturally high levels of leptin receptors may not gain weight as rapidly over time as people who have low levels of leptin receptors," said Dr. Unger. "It could explain why some people can eat more and do not gain weight." To test this hypothesis, the UT Southwestern researchers used genetically modified rats in which the leptin receptor remained present in large quantities even during marked overfeeding. In normal mice, the high-fat diet caused massive obesity with enlargement of fat cells to almost three times their normal size. In mice with the forced overexpression of the leptin receptor on their fat cells no obesity occurred, even though they too were fed high-fat, highly caloric diets.

"The fat-storing function of the fat cells requires the disappearance of the leptin receptor," Dr. Unger said. "This is done in order to block the action of the leptin fat cells produce."

May-Yun Wang, lead investigator and instructor of internal medicine at UT Southwestern, said the transgenic mice's high levels of leptin receptors caused all surplus calories to be burned rather than stored.

"They were overfed tremendously and did not get obese. Our control animals were fed the same diet and gained an enormous amount of weight," Dr. Wang said. "If we could prevent the disappearance of leptin receptors in people who overeat, they would likely not gain weight after overeating."

[dukey]

if obesity is genetic
someone took a giant shit in the gene pool of americans

[Tyler_JC]

Give me a break.





If it isn't obvious, you aren't paying attention.

Genetics don't give you an excuse to sit around and eat McBurgers with McMilkshakes without taking a walk around the block every now and then.

I just hope society puts a stop to this victim mentality bullshit and prevents obese people from becoming a protected minority group.

[HEADER_RACK]

They suffer from Anal-glaucoma.
They can't see their ass getting up and moving around

[Windmills]

You guys are ruining the transition to the drug pitch for the latest pill that is going to save all the helpless obese that are victims of genetics. If pharmaceutical companies don't flood the media with their pseudoscience advertising, the diet and exercise luddites might gain some traction in their market.

[vision-master]

$this->bbcode_second_pass_quote('Windmills', 'Y')ou guys are ruining the transition to the drug pitch for the latest pill that is going to save all the helpless obese that are victims of genetics. If pharmaceutical companies don't flood the media with their pseudoscience advertising, the diet and exercise luddites might gain some traction in their market.

[Tyler_JC]

Addicts in general irritate me. I don't care if it's junk food, crack, cigarettes, sex or whiskey.

Stop playing the victim card and take responsibility for your actions.

If you have a genetic predisposition towards addiction, it doesn't mean you have an excuse to be addicted forever. Some people have a genetic predisposition towards anti-social behavior, that doesn't mean we should tolerate their criminal activities.

The real problem is that some people use drugs, food, tobacco, etc. to cover up real psychological disorders.

Instead of treating their depression or anxiety disorder, they overeat.

[vision-master]

$this->bbcode_second_pass_quote('Tyler_JC', 'A')ddicts in general irritate me. I don't care if it's junk food, crack, cigarettes, sex or whiskey.

Stop playing the victim card and take responsibility for your actions.

If you have a genetic predisposition towards addiction, it doesn't mean you have an excuse to be addicted forever. Some people have a genetic predisposition towards anti-social behavior, that doesn't mean we should tolerate their criminal activities.

The real problem is that some people use drugs, food, tobacco, etc. to cover up real psychological disorders.

Instead of treating their depression or anxiety disorder, they overeat.

[ravensburg]

Sweet I can sit on my ass and watch more TV, drink more soda and eat greater amounts of fast food. When my ass ballons up a couple of sizes I can bitch at my parents for giveing me such crappy genes. God I love this country.

[vision-master]

$this->bbcode_second_pass_quote('ravensburg', 'S')weet I can sit on my ass and watch more TV, drink more soda and eat greater amounts of fast food. When my ass ballons up a couple of sizes I can bitch at my parents for giveing me such crappy genes. God I love this country.

[cowuvula]

In the WWII, there were no fat Jews in the camps.

Eating too much may be genetic.

Or it could be social.

http://www.jewishvirtuallibrary.org/jso ... st/o20.jpg

http://www.jewishvirtuallibrary.org/ima ... hwitz4.jpg

[IslandCrow]

After reading endless posts about solvent green, and treating them as a 'doomer wet dream' I just came across this on the BBC:

$this->bbcode_second_pass_quote('', 'F')our people have been arrested in Peru on suspicion of killing dozens of people in order to sell their fat and tissue for cosmetic uses in Europe.

The gang allegedly targeted people on remote roads, luring them with fake job offers before extracting their fat to sell it for $15,000 (£9,000) a litre.

[Pretorian]

who in the world would pay that much for human fat... Most common fat on the planet.. Can't you get it from cadavers if you really longed that fancy face cream?

[Sixstrings]

$this->bbcode_second_pass_quote('', '[')img]http://i.dailymail.co.uk/i/pix/2012/04/01/article-2123700-0F3DA26400000578-216_634x456.jpg[/img]
Overweight mothers-to-be are being allowed to take diabetes drugs to treat their unborn children in the womb to prevent them being born obese

Babies treated in the womb for obesity: Overweight mothers-to-be get diabetes pill to cut the risk of having a fat child

If the strategy is a success, the treatment could be in widespread use in as little as five years, with tens of thousands of overweight but otherwise healthy mothers-to-be drugged each year.

The Daily Mail recently revealed the rise of the 'sumo baby', with the number of newborns weighing more than 11lb soaring by 50 per cent over the last four years.

More than 15 per cent of pregnant women are obese. This raises their odds of dying in pregnancy, of their baby being stillborn and of a host of pregnancy complications, some of which can be fatal.

Big babies are around twice as likely to grow into overweight adults, suggesting obesity and the lifetime of ill-health it can bring is 'programmed' in the womb. The trial involves 400 pregnant women in Liverpool, Coventry, Sheffield and Edinburgh.

They have started taking metformin, which has been safely used by diabetics for decades and is cleared for the treatment of diabetes in pregnancy.


Research shows big babies are around twice as likely to grow into overweight adults
http://www.dailymail.co.uk/health/article-2123700/Babies-treated-womb-obesity-Overweight-mothers-diabetes-pill-cut-risk-having-fat-child.html

[vision-master]

Another fat ppl thread......... flame on Mrs. Johnson

When will this thread turn partisan and self-self righteous?

[Sixstrings]

$this->bbcode_second_pass_quote('vision-master', 'A')nother fat ppl thread......... flame on Mrs. Johnson

When will this thread turn partisan and self-self righteous?

[PrestonSturges]

Does this placenta make me look fat?

[Subjectivist]

http://www.npr.org/blogs/health/2011/06 ... -the-chips

Interesting piece from npr, once again the low carb eating plan works better for weight and waist loss and comenserate health improvements.

[dinopello]

Investors see fat profits in US obesity epidemic. See what they did there ?

$this->bbcode_second_pass_quote('', 'S')ome 84 million people in the U.S. struggle with obesity, a growing trend. In 2012, 35 percent of adults were obese, compared with only 14 percent in 1980, according to a National Health and Nutrition Survey. And estimates point to a larger girth in the future. Globally, more than 500 million people are obese, according to the World Health Organization. That number is slated to more than double by 2030.


"Diet and exercise aren't effective," said William Plovanic, medical technology equity research analyst at Canaccord Genuity.